A Novel Nanocomposite with Superior Antibacterial Activity: A Silver‐Based Metal-Organic Framework Embellished with Graphene Oxide
    Mostafa Dadashi Firouzjaei, Ahmad Arabi Shamsabadi,  Mohammad Sharifian Gh., Ahmad Rahimpour, and Masoud Soroush
Silver‐based nanomaterials have attracted considerable attention due to their antimicrobial activities. In this work, a silver (Ag)‐based metal organic framework (Ag‐MOF) is embellished with graphene‐oxide (GO), leading to the fabrication of a novel Ag‐based nanocomposite (GO‐Ag‐MOF) whose biocidal activity is higher than those of Ag‐MOF and GO nanomaterials. The nanocomposite is characterized using X‐ray photoelectron spectroscopy, transmission electron microscopy, scanning electron microscope, Fourier transform infrared spectra, ultraviolet−visible absorption spectra, X‐ray powder diffraction, dynamic light scattering, and nitrogen gas adsorption/desorption. The characterization shows that the Ag‐MOF nanoparticles are uniformly dispersed on the GO nanosheets surfaces without any agglomeration. Toxicities of GO‐Ag‐MOF, Ag‐MOF, and GO are assessed against the Gram‐negative bacteria, Escherichia coli and the Gram‐positive bacteria, Bacillus subtilis using the growth curve, fluorescence imaging, and flow cytometry methods. GO‐Ag‐MOF shows an outstanding antibacterial activity (higher than those of the Ag‐MOF and GO alone). The interaction of GO‐Ag‐MOF and Ag‐MOF with the bacteria leads to the extirpation of 95 and 85% of live bacteria cells, respectively. This study indicates that GO‐Ag‐MOF is a promising antibacterial nanocomposite, especially for biomedical applications.
                             Type                         Experimental
                             Publication           Advanced Materials Interfaces 
                             Date                          April 2018
                             Links                        URL
silver, antibacterial, powder, metal-organic framework, nanocomposite, chemical
chemistry, E. coli, water, 3D structure, bacteria

@article{firouzjaei2018novel, title={A novel nanocomposite with superior antibacterial activity: a silver-based metal organic framework embellished with graphene oxide}, author={Firouzjaei, Mostafa Dadashi and Shamsabadi, Ahmad Arabi and Sharifian Gh, Mohammad and Rahimpour, Ahmad and Soroush, Masoud}, journal={Advanced Materials Interfaces}, volume={5}, number={11}, pages={1701365}, year={2018}, publisher={Wiley Online Library} }